Many can and will be against us. We can't please everyone and honestly, we should not attempt to please everyone. If our goal in life is to please everyone, we most likely will do things that we shouldn't do and say things that we shouldn't say. If we are truly honest with ourselves and others, we will upset others and by human nature, those who we disagree with us will choose to be against us. God will always be for us if we choose Him and we should also love others, despite their choice to be against us.
Lord, help me to love others and regardless of their choice, thank you for always loving me.